Across TCGA patient cohorts, MUC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,706 significant associations in total. THYM shows the largest number of these associations.

The most reproducible MUC2-associated GO terms across cancer lineages are Lobar bronchus epithelium development, Negative regulation of peptidyl-threonine phosphorylation, and Negative regulation of receptor binding. Each is linked with MUC2 in more than 10 cancer types. Because this analysis shows association rather than direction, both MUC2-to-partner and partner-to-MUC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC2→partner) and Y-score (partner→MUC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Lobar bronchus epithelium development →	+0.282	+0.348	<.001	<.001	3	11
THYM	Negative regulation of peptidyl-threonine phosphorylation →	+0.081	+0.327	<.001	<.001	3	10
ESCA	Negative regulation of receptor binding →	+0.071	+2.299	<.001	<.001	3	10
TGCT	Lobar bronchus development →	+0.335	+0.347	<.001	<.001	3	10
TGCT	Notch signaling pathway →	+0.061	+0.662	<.001	<.001	3	10
THYM	Multicellular organismal-level water homeostasis →	+0.056	+0.321	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,706 associations by consensus.

Exploration

MUC2 survival (RNA) · tumor vs normal (RNA) · all MUC2 data types