Across TCGA patient cohorts, MUC2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,578 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MUC2-associated genes across cancer lineages are SCOC, CTSG, and GNPNAT1. Each is linked with MUC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MUC2-to-partner and partner-to-MUC2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC2→partner) and Y-score (partner→MUC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SCOC →	+0.496	+0.577	<.001	.003	3	2
COAD	CTSG →	+0.770	+1.039	.008	<.001	3	2
COAD	GNPNAT1 →	+0.836	+1.208	<.001	<.001	3	2
BRCA	CNIH1 →	+0.445	+1.157	.001	.003	3	2
BRCA	RAB11A →	+0.427	+1.388	.003	.003	3	2
BRCA	ABHD17B →	+0.405	+1.259	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,578 associations by consensus.

Exploration

MUC2 survival (RNA) · tumor vs normal (RNA) · all MUC2 data types