Across TCGA cell cohorts, MUC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,254 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MUC2-associated GO terms across cancer lineages are Regulation of clathrin coat assembly, Oocyte growth, and Cytoplasm protein quality control by the ubiquitin-proteasome system. Each is linked with MUC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MUC2-to-partner and partner-to-MUC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC2→partner) and Y-score (partner→MUC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of clathrin coat assembly →	+0.166	+1.788	<.001	.005	3	6
SOFT_TISSUE	Oocyte growth →	+0.143	+0.219	<.001	.007	3	5
BLOOD_Lymphoma	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.107	+0.021	<.001	.001	3	5
BLOOD_Leukemia	mRNA splice site recognition →	+0.052	+0.047	<.001	<.001	3	5
LARGE_INTESTINE	Response to lipoprotein particle →	+0.075	+1.844	<.001	<.001	3	5
LARGE_INTESTINE	2-oxoglutarate metabolic process →	+0.102	+1.794	.003	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,254 associations by consensus.

Exploration

MUC2 survival (RNA) · tumor vs normal (RNA) · all MUC2 data types