MUC15

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MUC15 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,512 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MUC15-associated proteins across cancer lineages are MAP2, UHRF1BP1L, and ARHGAP44. Each is linked with MUC15 in more than 3 cancer types. Because this analysis shows association rather than direction, both MUC15-to-partner and partner-to-MUC15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC15 versus MAP2 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC15→partner) and Y-score (partner→MUC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMAP2 →+0.579+0.250<.001<.00134
BRCAUHRF1BP1L →-0.185-1.199<.001<.00133
GBMARHGAP44 →+0.790+0.356<.001.00133
BRCAPHGDH →+0.732+1.229<.001<.00133
CCRCCPID1 →+0.530+0.800<.001<.00133
GBMPIGS →-0.200-0.287.002.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,512 associations by consensus.

MUC15 vs MAP2 — GBM

Per-sample scatter of MUC15 vs MAP2 in GBM (Pearson r = 0.46).

Explore this scatter interactively →

Exploration