MUC15

Across TCGA patient cohorts, MUC15 protein abundance is significantly associated with the RNA expression of many other genes, with 1,505 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MUC15-associated genes across cancer lineages are APBA1, DISC1, and TLE4. Each is linked with MUC15 in more than 1 cancer types. Because this analysis shows association rather than direction, both MUC15-to-partner and partner-to-MUC15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC15 versus APBA1 in LUAD, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC15→partner) and Y-score (partner→MUC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	APBA1 →	+0.483	+0.479	.009	.003	3	2
HNSC	DISC1 →	-0.612	-0.958	.003	.006	3	2
CCRCC	TLE4 →	+0.646	+0.463	.002	.006	3	2
CCRCC	SETX →	+0.415	+0.486	.001	.005	3	2
LSCC	TOR1A →	+0.378	+0.752	.001	<.001	3	2
LUAD	ZDHHC2 →	-0.506	-0.811	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,505 associations by consensus.

MUC15 vs APBA1 — LUAD

Explore this scatter interactively →