MUC15

Across TCGA cell cohorts, MUC15 RNA expression is significantly associated with the go_rna of many other GO terms, with 826 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MUC15-associated GO terms across cancer lineages are Endosome to lysosome transport, Viral transcription, and Vesicle-mediated transport to the plasma membrane. Each is linked with MUC15 in more than 5 cancer types. Because this analysis shows association rather than direction, both MUC15-to-partner and partner-to-MUC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosome to lysosome transport grouped by MUC15-low versus MUC15-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC15→partner) and Y-score (partner→MUC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Endosome to lysosome transport →	+0.053	+0.925	<.001	.005	3	5
OESOPHAGUS	Viral transcription →	+0.066	+0.843	.003	.009	3	5
LUNG_NSCLC_LUAD	Vesicle-mediated transport to the plasma membrane →	+0.031	+1.111	.006	.002	2	6
OVARY	Cell surface receptor signaling pathway via STAT →	-0.048	-1.125	.006	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Negative regulation of inclusion body assembly →	+0.120	+1.305	.006	.006	2	5
LUNG_SCLC	Foam cell differentiation →	-0.166	-2.239	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 826 associations by consensus.

Endosome to lysosome transport by MUC15 expression — OVARY

Explore this box plot interactively →