Across TCGA patient cohorts, MUC1 RNA expression is significantly associated with the RNA expression of many other genes, with 16,599 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible MUC1-associated genes across cancer lineages are MROH6, SCNN1A, and CFB. Each is linked with MUC1 in more than 27 cancer types. Because this analysis shows association rather than direction, both MUC1-to-partner and partner-to-MUC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC1→partner) and Y-score (partner→MUC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	MROH6 →	+1.413	+1.554	<.001	<.001	3	28
CHOL	SCNN1A →	+3.030	+2.995	<.001	<.001	2	28
ESCA	CFB →	+2.046	+2.822	<.001	<.001	3	26
UCS	THBS3-AS1 →	+0.875	+2.107	.005	.005	2	27
UVM	BCL3 →	+1.143	+0.511	<.001	<.001	3	26
UCS	ADAM8 →	+1.602	+2.792	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,599 associations by consensus.

Exploration

MUC1 survival (RNA) · tumor vs normal (RNA) · all MUC1 data types