MTX1

Across TCGA cell cohorts, MTX1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,780 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MTX1-associated genes across cancer lineages are PSMB4, SCAMP3, and DAP3. Each is linked with MTX1 in more than 18 cancer types. Because this analysis shows association rather than direction, both MTX1-to-partner and partner-to-MTX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTX1 versus PSMB4 in LUNG_SCLC, with a Pearson correlation of 0.48.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTX1→partner) and Y-score (partner→MTX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PSMB4 →	+1.004	+0.956	<.001	<.001	2	19
LIVER	SCAMP3 →	+1.169	+0.681	<.001	<.001	3	18
LUNG_NSCLC_LUSC	DAP3 →	+0.814	+0.715	.001	<.001	3	18
BREAST	SNAPIN →	+0.909	+0.677	<.001	<.001	3	18
BLOOD_Myeloma	PMF1 →	+1.306	+1.076	<.001	<.001	3	18
LUNG_NSCLC_LUSC	TOMM40L →	+1.357	+0.671	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,780 associations by consensus.

MTX1 vs PSMB4 — LUNG_SCLC

Explore this scatter interactively →