MTUS2-AS2

Across TCGA pan-cancer cohorts, MTUS2-AS2 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MTUS2-AS2 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher MTUS2-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTUS2-AS2 expression acts as an unfavorable survival marker, although some lineages such as UCS and KICH show a favorable association.

READ, UCS, and KIRC are the cancer types where MTUS2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	II,III,IV	0.178	0.651	.001	99	view →
UCS	OS	Median	II,III,IV	0.601	0.218	.003	74	view →
KIRC	DFS	Tertile	All	0.364	0.681	<.001	54	view →
KICH	DFS	Median	II,III,IV	0.921	0.577	.006	49	view →
DLBC	OS	Quartile	II,III,IV	0.257	1.000	.001	46	view →
COAD	OS	Tertile	III,IV	0.142	0.791	.003	24	view →
CESC	OS	Tertile	IV	0.235	0.606	.044	18	view →
LIHC	OS	Tertile	III,IV	0.051	0.616	<.001	18	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	9	view →
LAML	DFS	Quartile	All	0.686	0.405	.040	4	view →
LGG	DFS	Tertile	All	0.321	0.414	.032	3	view →
STAD	DFS	Quartile	IV	0.160	0.402	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

MTUS2-AS2–READ (OS)

Open the READ breakdown →