MTUS2-AS2

Across TCGA pan-cancer cohorts, MTUS2-AS2 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MTUS2-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MTUS2-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTUS2-AS2 is over-expressed in tumor, although a few such as BRCA and PAAD show the opposite, repressed pattern.

KICH, BRCA, and PAAD are the cancer types where MTUS2-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTUS2-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.211	.003	4	view →
BRCA	Female	All	−0.064	<.001	4	view →
PAAD	Male	All	−0.090	.012	2	view →
UCEC	All	All	−0.023	.022	2	view →
KIRC	All	All	+0.015	.018	2	view →
LUSC	All	All	+0.072	.029	1	view →
LIHC	All	All	−0.013	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MTUS2-AS2–KICH

Open the KICH breakdown →