MTUS1

Across TCGA pan-cancer cohorts, MTUS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MTUS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MTUS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTUS1 is over-expressed in tumor, although a few such as COAD and KIRC show the opposite, repressed pattern.

THCA, COAD, and KIRC are the cancer types where MTUS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTUS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	III,IV	+0.884	<.001	10	view →
COAD	Female	All	−1.210	<.001	9	view →
KIRC	Male	III,IV	−0.697	<.001	8	view →
KIRP	Male	All	−1.126	<.001	7	view →
BRCA	Female	All	−0.547	<.001	6	view →
LUSC	Male	All	−0.737	<.001	5	view →
CHOL	All	All	+1.045	.003	2	view →
READ	All	All	−1.017	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

MTUS1–THCA

Open the THCA breakdown →