MTRNR2L5

Across TCGA pan-cancer cohorts, MTRNR2L5 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MTRNR2L5 data layer.

The strongest signal is observed in small cell lung cancer (SCLC), where higher MTRNR2L5 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MTRNR2L5 expression acts as an unfavorable survival marker, although some lineages such as SCLC and MESO show a favorable association.

SCLC, MESO, and KIRP are the cancer types where MTRNR2L5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Quartile	All	0.569	0.254	.003	38	view →
MESO	OS	Tertile	III,IV	0.781	0.517	.019	24	view →
KIRP	DFS	Tertile	All	1.000	0.827	.018	21	view →
LGG	OS	Quartile	All	0.897	0.755	<.001	19	view →
ESCA	OS	Median	III,IV	0.525	0.307	.008	18	view →
LUAD	DFS	Quartile	IV	0.464	0.777	.016	18	view →
OV	OS	Quartile	III,IV	0.894	0.803	.025	12	view →
ACC	DFS	Quartile	All	0.787	0.474	.011	12	view →
SKCM	DFS	Quartile	III,IV	0.843	0.578	.018	10	view →
READ	DFS	Tertile	IV	0.403	0.704	.024	9	view →
PAAD	DFS	Tertile	III,IV	0.357	0.908	.038	6	view →
COAD	OS	Tertile	IV	0.257	0.560	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MTRNR2L5–SCLC (OS)

Open the SCLC breakdown →