MTRNR2L5

Across TCGA pan-cancer cohorts, MTRNR2L5 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MTRNR2L5’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where MTRNR2L5 RNA is repressed in tumor relative to normal tissue. In most cancer types MTRNR2L5 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.

READ, KICH, and LIHC are the cancer types where MTRNR2L5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTRNR2L5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	All	II,III,IV	−0.077	.030	3	view →
KICH	Male	All	+0.060	.007	3	view →
LIHC	Female	All	+0.037	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MTRNR2L5–READ

Open the READ breakdown →