MTRNR2L4

Across TCGA patient cohorts, MTRNR2L4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,135 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTRNR2L4-associated GO terms across cancer lineages are Intracellular estrogen receptor signaling pathway, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Stress granule assembly. Each is linked with MTRNR2L4 in more than 30 cancer types. Because this analysis shows association rather than direction, both MTRNR2L4-to-partner and partner-to-MTRNR2L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular estrogen receptor signaling pathway grouped by MTRNR2L4-low versus MTRNR2L4-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTRNR2L4→partner) and Y-score (partner→MTRNR2L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Intracellular estrogen receptor signaling pathway →	+0.151	+0.680	<.001	<.001	3	31
SCLC	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.116	+0.609	<.001	<.001	3	30
ESCA	Stress granule assembly →	+0.080	+0.302	<.001	<.001	3	30
STAD	Regulation of RNA splicing →	+0.068	+0.193	<.001	<.001	3	30
SCLC	Vesicle tethering →	+0.089	+0.495	<.001	<.001	3	30
SCLC	Telomere maintenance via telomere lengthening →	+0.078	+0.486	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,135 associations by consensus.

Intracellular estrogen receptor signaling pathway by MTRNR2L4 expression — SCLC

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