MTRES1

Across TCGA pan-cancer cohorts, MTRES1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MTRES1 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MTRES1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MTRES1 expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, HNSC, and CCRCC are the cancer types where MTRES1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	1.000	0.823	.015	48	view →
HNSC	DFS	Median	IV	0.503	0.814	.001	28	view →
CCRCC	DFS	Median	II,III,IV	0.441	0.799	.001	15	view →
GBM	DFS	Quartile	All	0.440	0.209	.007	11	view →
LSCC	OS	Median	All	1.000	0.934	.013	9	view →
PDAC	DFS	Tertile	All	0.199	0.370	.026	5	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MTRES1–COAD (DFS)

Open the COAD breakdown →