MTO1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MTO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,227 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MTO1-associated proteins across cancer lineages are CDC40, LPCAT3, and SCAF8. Each is linked with MTO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTO1-to-partner and partner-to-MTO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTO1 versus CDC40 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTO1→partner) and Y-score (partner→MTO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCDC40 →+0.274+0.481<.001<.00136
CCRCCLPCAT3 →-0.615-0.241<.001.00136
LSCCSCAF8 →+0.221+0.467<.001<.00135
BRCASMAP1 →+0.302+0.292<.001<.00135
LSCCGATAD2B →+0.296+0.361<.001<.00135
GBMPHF3 →+0.281+0.376<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,227 associations by consensus.

MTO1 vs CDC40 — LSCC

Per-sample scatter of MTO1 vs CDC40 in LSCC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration