MTNR1A

Across TCGA cell cohorts, MTNR1A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,426 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MTNR1A-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Protein-RNA complex organization. Each is linked with MTNR1A in more than 7 cancer types. Because this analysis shows association rather than direction, both MTNR1A-to-partner and partner-to-MTNR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by MTNR1A-low versus MTNR1A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTNR1A→partner) and Y-score (partner→MTNR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of myoblast fusion →	+0.091	+0.304	.003	.003	3	8
PANCREAS	Regulation of myoblast fusion →	+0.093	+0.314	.003	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Protein-RNA complex organization →	+0.051	+0.227	.001	.001	3	7
PANCREAS	Negative regulation of RNA catabolic process →	+0.042	+0.213	.001	.005	3	7
PANCREAS	Nuclear-transcribed mRNA catabolic process →	+0.033	+0.269	.003	.004	3	6
UPPER_AERODIGESTIVE_TRACT	Nucleic acid catabolic process →	+0.046	+0.172	.002	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,426 associations by consensus.

Negative regulation of myoblast fusion by MTNR1A expression — PANCREAS

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