MTND5P16

Across TCGA pan-cancer cohorts, MTND5P16 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTND5P16 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MTND5P16 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND5P16 expression acts as an unfavorable survival marker, although some lineages such as LGG and ACC show a favorable association.

UCS, MESO, and UVM are the cancer types where MTND5P16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
MESO	DFS	Tertile	III,IV	0.106	0.381	.028	18	view →
UVM	OS	Tertile	All	0.248	0.769	.007	18	view →
LUAD	OS	Tertile	All	0.342	0.687	.002	18	view →
LIHC	DFS	Tertile	III,IV	0.088	0.337	.002	18	view →
OV	OS	Median	IV	0.645	0.847	.005	16	view →
LGG	OS	Tertile	All	0.567	0.417	.005	15	view →
THYM	OS	Tertile	All	0.381	0.878	.017	12	view →
PCPG	OS	Tertile	All	0.939	1.000	.034	9	view →
ACC	DFS	Tertile	III,IV	1.000	0.405	.045	6	view →
SKCM	OS	Tertile	All	1.000	0.775	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTND5P16–UCS (DFS)

Open the UCS breakdown →