MTND5P14

Across TCGA pan-cancer cohorts, MTND5P14 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MTND5P14 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MTND5P14 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND5P14 expression acts as an unfavorable survival marker, although some lineages such as BRCA and PAAD show a favorable association.

UVM, THYM, and COAD are the cancer types where MTND5P14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.037	0.835	<.001	54	view →
THYM	OS	Tertile	II,III,IV	0.692	1.000	<.001	54	view →
COAD	OS	Tertile	IV	0.284	0.708	<.001	45	view →
DLBC	DFS	Tertile	III,IV	0.074	0.984	.017	31	view →
READ	OS	Tertile	III,IV	0.194	0.914	<.001	27	view →
ACC	DFS	Tertile	IV	0.119	0.477	.005	27	view →
KIRP	DFS	Tertile	III,IV	0.390	0.789	.002	21	view →
OV	OS	Median	All	0.791	0.884	.008	20	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
KICH	DFS	Tertile	All	0.481	0.919	.005	18	view →
BRCA	DFS	Median	III,IV	0.600	0.385	.003	12	view →
UCS	DFS	Tertile	All	0.228	0.475	.019	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MTND5P14–UVM (OS)

Open the UVM breakdown →