MTND5P12

Across TCGA pan-cancer cohorts, MTND5P12 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MTND5P12 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher MTND5P12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND5P12 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LAML show a favorable association.

TGCT, BLCA, and LUAD are the cancer types where MTND5P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	DFS	Tertile	II,III,IV	0.586	0.996	.002	36	view →
BLCA	DFS	Tertile	All	0.742	0.507	.019	34	view →
LUAD	OS	Median	III,IV	0.496	0.761	.008	34	view →
LAML	DFS	Tertile	All	0.690	0.437	.002	30	view →
CHOL	DFS	Tertile	All	0.093	0.536	.009	27	view →
KICH	DFS	Median	All	0.941	0.729	.021	26	view →
UVM	DFS	Median	All	0.320	0.671	.008	24	view →
ESCA	OS	Tertile	III,IV	0.696	0.298	.013	16	view →
ACC	DFS	Median	All	0.593	0.319	.006	14	view →
UCS	DFS	Tertile	IV	0.981	0.586	.031	12	view →
OV	OS	Quartile	All	0.269	0.440	.009	8	view →
LGG	DFS	Quartile	All	0.638	0.830	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MTND5P12–TGCT (DFS)

Open the TGCT breakdown →