Across TCGA pan-cancer cohorts, MTND4P23 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MTND4P23’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where MTND4P23 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND4P23 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

STAD, LUSC, and KIRC are the cancer types where MTND4P23 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND4P23 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.206	.008	4	view →
LUSC	All	All	−0.082	.001	4	view →
KIRC	All	All	+0.046	.004	4	view →
CHOL	All	II,III,IV	+0.505	.007	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MTND4P23 RNA expression & survival · all MTND4P23 data types