MTND4P16

Across TCGA pan-cancer cohorts, MTND4P16 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MTND4P16’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where MTND4P16 RNA is repressed in tumor relative to normal tissue. In most cancer types MTND4P16 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

UCEC, BRCA, and STAD are the cancer types where MTND4P16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND4P16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	II,III,IV	−0.040	.044	2	view →
BRCA	All	III,IV	−0.018	.037	2	view →
STAD	Male	All	+0.049	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MTND4P16–UCEC

Open the UCEC breakdown →