MTND4LP7

Across TCGA pan-cancer cohorts, MTND4LP7 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MTND4LP7 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MTND4LP7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND4LP7 expression acts as an unfavorable survival marker, although some lineages such as LIHC and BRCA show a favorable association.

UVM, MESO, and COAD are the cancer types where MTND4LP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.055	0.692	<.001	63	view →
MESO	OS	Tertile	III,IV	0.200	0.607	<.001	54	view →
COAD	DFS	Tertile	II,III,IV	0.203	0.513	.002	45	view →
READ	DFS	Tertile	IV	0.168	0.640	<.001	36	view →
OV	OS	Tertile	All	0.233	0.345	.003	24	view →
LUSC	OS	Tertile	II,III,IV	0.477	0.798	.026	18	view →
TGCT	DFS	Tertile	All	0.707	0.850	.015	18	view →
LIHC	DFS	Tertile	II,III,IV	1.000	0.419	.016	18	view →
PCPG	OS	Tertile	All	0.720	0.958	.007	15	view →
KIRC	DFS	Tertile	III,IV	0.639	0.775	.028	12	view →
THCA	OS	Tertile	IV	0.813	1.000	.039	12	view →
STAD	DFS	Median	II,III,IV	0.524	0.690	.004	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MTND4LP7–UVM (DFS)

Open the UVM breakdown →