MTND4LP21

Across TCGA pan-cancer cohorts, MTND4LP21 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MTND4LP21 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MTND4LP21 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND4LP21 expression acts as an unfavorable survival marker, although some lineages such as LAML and LUSC show a favorable association.

UCS, CHOL, and STAD are the cancer types where MTND4LP21 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.001	0.690	<.001	108	view →
CHOL	OS	Tertile	All	0.024	0.728	<.001	108	view →
STAD	OS	Tertile	IV	0.125	0.614	<.001	48	view →
ESCA	OS	Tertile	All	0.205	0.911	<.001	36	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	36	view →
SARC	OS	Tertile	All	0.022	0.861	<.001	36	view →
KIRC	DFS	Tertile	All	0.306	0.634	.019	24	view →
LAML	DFS	Median	All	0.526	0.242	.019	20	view →
COAD	OS	Tertile	III,IV	0.140	0.780	.004	18	view →
ACC	OS	Tertile	All	0.147	0.685	.018	18	view →
GBM	DFS	Tertile	All	0.056	0.244	.003	9	view →
HNSC	DFS	Tertile	IV	0.163	0.669	.033	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MTND4LP21–UCS (OS)

Open the UCS breakdown →