Q-omics provides the consensus-scored MTND3P8 profile across patient tissues and cancer cell-line models. MTND3P8 expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, MTND3P8 is differentially expressed in 1, with the highest sampling consensus in STAD. Additionally, MTND3P8 RNA expression shows 6,962 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight SKCM, STAD, and COAD as cancer lineages where MTND3P8 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND3P8 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND3P8 survival associations across molecular data types. MTND3P8 RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND3P8 RNA expression–survival associations across cancer types. High MTND3P8 expression shows unfavorable associations in SKCM, TGCT and PRAD, but favorable associations in STAD. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify SKCM as the clearest survival context for MTND3P8 RNA expression.
This table summarizes MTND3P8 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for MTND3P8. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND3P8 shows higher tumor expression in STAD. The STAD box plot shows higher MTND3P8 RNA expression in tumor versus normal tissue (log2 FC = +0.040, t-test p = .025).
This table shows molecular features associated with MTND3P8 in patient tissues and cancer cell lines. In patient samples, MTND3P8 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
