MTND2P21

Across TCGA pan-cancer cohorts, MTND2P21 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTND2P21’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MTND2P21 RNA is repressed in tumor relative to normal tissue. In most cancer types MTND2P21 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.

LIHC and KICH are the cancer types where MTND2P21 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND2P21 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	−0.013	.004	4	view →
KICH	Female	All	+0.042	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MTND2P21–LIHC

Open the LIHC breakdown →