Across TCGA pan-cancer cohorts, MTND1P6 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTND1P6’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where MTND1P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND1P6 is over-expressed in tumor.
THCA and KICH are the cancer types where MTND1P6 tumor–normal differential expression is most reproducible.