MTND1P26

Across TCGA pan-cancer cohorts, MTND1P26 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MTND1P26 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher MTND1P26 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND1P26 expression acts as an unfavorable survival marker, although some lineages such as LAML and SKCM show a favorable association.

ESCA, CESC, and DLBC are the cancer types where MTND1P26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	II,III,IV	0.336	0.566	.001	91	view →
CESC	DFS	Tertile	II,III,IV	0.143	0.716	<.001	72	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →
PRAD	DFS	Tertile	All	0.872	0.936	.007	18	view →
THCA	DFS	Tertile	II,III,IV	0.648	0.876	.034	12	view →
LAML	DFS	Median	All	0.767	0.461	.008	12	view →
SARC	OS	Tertile	All	0.504	0.864	.004	9	view →
SKCM	DFS	Tertile	All	1.000	0.740	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MTND1P26–ESCA (DFS)

Open the ESCA breakdown →