Across TCGA pan-cancer cohorts, MTND1P14 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTND1P14’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MTND1P14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND1P14 is over-expressed in tumor, although a few such as BRCA and CHOL show the opposite, repressed pattern.

LIHC, BRCA, and CHOL are the cancer types where MTND1P14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND1P14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.085	<.001	4	view →
BRCA	All	II,III,IV	−0.014	.026	4	view →
CHOL	All	II,III,IV	−0.100	.009	2	view →
THCA	Female	All	+0.044	.003	2	view →
HNSC	All	II,III,IV	+0.007	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MTND1P14 RNA expression & survival · all MTND1P14 data types