MTMR8

Across TCGA patient cohorts, MTMR8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,266 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MTMR8-associated proteins across cancer lineages are EPB41L2, RASAL3, and RASSF5. Each is linked with MTMR8 in more than 4 cancer types. Because this analysis shows association rather than direction, both MTMR8-to-partner and partner-to-MTMR8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTMR8 versus EPB41L2 in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR8→partner) and Y-score (partner→MTMR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EPB41L2 →	+0.496	+1.243	<.001	<.001	3	5
GBM	RASAL3 →	+0.356	+0.482	<.001	<.001	3	4
BRCA	RASSF5 →	+0.475	+0.353	<.001	.001	3	4
PDAC	PEBP1 →	+0.337	+0.327	<.001	<.001	3	4
GBM	GYG1 →	+0.386	+0.720	<.001	<.001	3	4
CCRCC	SH3BP1 →	+0.320	+0.395	.004	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,266 associations by consensus.

MTMR8 vs EPB41L2 — UCEC

Explore this scatter interactively →