MTMR8

Across TCGA cell cohorts, MTMR8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,286 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTMR8-associated GO terms across cancer lineages are Regulation of cell cycle G2/M phase transition, Regulation of G1/S transition of mitotic cell cycle, and DNA strand elongation. Each is linked with MTMR8 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTMR8-to-partner and partner-to-MTMR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle G2/M phase transition grouped by MTMR8-low versus MTMR8-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR8→partner) and Y-score (partner→MTMR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of cell cycle G2/M phase transition →	+0.056	+0.375	.003	.001	3	6
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.047	+0.555	<.001	.001	3	6
BLOOD_Leukemia	DNA strand elongation →	+0.084	+0.651	<.001	<.001	3	6
BLOOD_Leukemia	Nucleosome organization →	+0.072	+0.573	<.001	<.001	3	6
BLOOD_Lymphoma	Cell cycle phase transition →	+0.057	+0.596	<.001	.001	3	6
BLOOD_Leukemia	Sister chromatid cohesion →	+0.080	+0.564	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,286 associations by consensus.

Regulation of cell cycle G2/M phase transition by MTMR8 expression — BREAST

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