MTMR7

Across TCGA patient cohorts, MTMR7 mutation is significantly associated with the RNA expression of many other genes, with 2,912 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTMR7-associated genes across cancer lineages are MIPEPP2, SHC1P1, and YY1P2. Each is linked with MTMR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTMR7-to-partner and partner-to-MTMR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIPEPP2 grouped by MTMR7-low versus MTMR7-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR7→partner) and Y-score (partner→MTMR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIPEPP2 →	+0.038	+4.812	<.001	.006	3	2
BLCA	SHC1P1 →	+0.024	+3.130	.001	.007	3	2
LUAD	YY1P2 →	+0.035	+4.399	<.001	.008	3	2
LUAD	LCE6A →	+0.047	+5.000	<.001	.003	3	2
LUAD	HIGD1AP15 →	+0.213	+4.157	<.001	.003	3	2
COAD	C1QBPP1 →	+0.115	+4.868	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,912 associations by consensus.

MIPEPP2 by MTMR7 expression — CESC

Explore this box plot interactively →