MTMR7

Across TCGA pan-cancer cohorts, MTMR7 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated MTMR7 data layer compared with 7 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher MTMR7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTMR7 expression acts as an unfavorable survival marker, although some lineages such as LGG and PAAD show a favorable association.

KICH, STAD, and LGG are the cancer types where MTMR7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	II,III,IV	0.561	0.921	.002	89	view →
STAD	DFS	Tertile	III,IV	0.301	0.617	.001	51	view →
LGG	DFS	Median	All	0.499	0.309	<.001	49	view →
PAAD	DFS	Tertile	All	0.404	0.187	.001	43	view →
MESO	DFS	Quartile	II,III,IV	0.269	0.557	.009	43	view →
ACC	DFS	Median	IV	0.056	0.430	.001	41	view →
LAML	DFS	Tertile	All	0.538	0.271	.002	36	view →
KIRC	DFS	Tertile	II,III,IV	0.402	0.595	.006	26	view →
KIRP	DFS	Median	All	0.567	0.924	.001	24	view →
UVM	OS	Median	III,IV	0.304	1.000	.008	21	view →
LUAD	DFS	Tertile	All	0.640	0.268	.007	21	view →
SKCM	DFS	Tertile	All	0.272	0.158	.005	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

MTMR7–KICH (DFS)

Open the KICH breakdown →