MTMR7

Across TCGA cell cohorts, MTMR7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,001 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MTMR7-associated GO terms across cancer lineages are Regulation of maintenance of sister chromatid cohesion, Regulation of maintenance of mitotic sister chromatid cohesion, and Regulation of microtubule cytoskeleton organization. Each is linked with MTMR7 in more than 12 cancer types. Because this analysis shows association rather than direction, both MTMR7-to-partner and partner-to-MTMR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of maintenance of sister chromatid cohesion grouped by MTMR7-low versus MTMR7-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR7→partner) and Y-score (partner→MTMR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of maintenance of sister chromatid cohesion →	+0.088	+0.310	.001	.007	3	13
OESOPHAGUS	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.088	+0.310	.001	.007	3	13
LARGE_INTESTINE	Regulation of microtubule cytoskeleton organization →	+0.031	+0.231	.001	<.001	3	9
PANCREAS	Regulation of cell cycle G1/S phase transition →	+0.040	+0.378	.001	<.001	3	9
PANCREAS	Regulation of RNA splicing →	+0.053	+0.264	.001	.004	3	9
LUNG_SCLC	piRNA-mediated gene silencing by mRNA destabilization →	+0.280	+1.839	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,001 associations by consensus.

Regulation of maintenance of sister chromatid cohesion by MTMR7 expression — OESOPHAGUS

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