MTMR7

Across TCGA cell cohorts, MTMR7 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MTMR7-associated genes across cancer lineages are CD300H, NOBOX, and NPHS2. Each is linked with MTMR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTMR7-to-partner and partner-to-MTMR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by MTMR7-low versus MTMR7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR7→partner) and Y-score (partner→MTMR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.022	+3.192	<.001	.002	3	2
URINARY_TRACT	NOBOX →	+0.020	+5.044	<.001	<.001	3	1
URINARY_TRACT	NPHS2 →	+0.187	+5.044	<.001	<.001	3	1
URINARY_TRACT	CLEC14A →	+0.013	+4.217	.007	.005	3	1
URINARY_TRACT	TMEM252 →	+0.637	+4.217	<.001	.005	3	1
URINARY_TRACT	PRR23A →	+0.028	+4.584	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

CD300H by MTMR7 expression — LARGE_INTESTINE

Explore this box plot interactively →