MTMR12

Across TCGA cell cohorts, MTMR12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,543 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MTMR12-associated GO terms across cancer lineages are Response to rapamycin, Cellular response to rapamycin, and Cell adhesion molecule production. Each is linked with MTMR12 in more than 15 cancer types. Because this analysis shows association rather than direction, both MTMR12-to-partner and partner-to-MTMR12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to rapamycin grouped by MTMR12-low versus MTMR12-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR12→partner) and Y-score (partner→MTMR12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Response to rapamycin →	+0.134	+1.292	.001	<.001	3	16
OVARY	Cellular response to rapamycin →	+0.146	+0.860	.001	.002	2	15
BONE	Cell adhesion molecule production →	+0.157	+0.832	.003	<.001	3	12
OVARY	Establishment of mitotic sister chromatid cohesion →	+0.102	+0.858	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to nuclear inner membrane →	+0.183	+1.136	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of RNA export from nucleus →	+0.089	+0.833	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,543 associations by consensus.

Response to rapamycin by MTMR12 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →