MTMR1

Across TCGA patient cohorts, MTMR1 mutation is significantly associated with the RNA expression of many other genes, with 3,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTMR1-associated genes across cancer lineages are RNU6-1216P, RN7SL210P, and ATF4P1. Each is linked with MTMR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MTMR1-to-partner and partner-to-MTMR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1216P grouped by MTMR1-low versus MTMR1-high in DLBC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTMR1→partner) and Y-score (partner→MTMR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	RNU6-1216P →	+0.441	+4.874	<.001	.008	3	3
DLBC	RN7SL210P →	+0.190	+4.874	<.001	.008	3	2
SKCM	ATF4P1 →	+0.031	+3.180	<.001	.004	3	2
SKCM	HCFC2P1 →	+0.100	+2.915	<.001	.008	3	2
BLCA	RNU6-177P →	+0.291	+3.623	.007	.004	3	2
BLCA	RNU6-62P →	+0.637	+3.069	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,064 associations by consensus.

RNU6-1216P by MTMR1 expression — DLBC

Explore this box plot interactively →