MTIF3

Across TCGA patient cohorts, MTIF3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,467 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MTIF3-associated genes across cancer lineages are MTF2, MT-CO2, and MT-CYB. Each is linked with MTIF3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MTIF3-to-partner and partner-to-MTIF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTIF3 versus MTF2 in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTIF3→partner) and Y-score (partner→MTIF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTF2 →	-0.438	-0.236	<.001	<.001	3	5
PDAC	MT-CO2 →	+0.578	+0.202	.001	.003	3	5
COAD	MT-CYB →	+0.675	+0.437	<.001	<.001	3	5
PDAC	SUGCT-AS1 →	-0.655	-0.258	<.001	<.001	3	5
COAD	GTF3A →	+0.596	+0.365	<.001	<.001	3	5
OV	ENO2 →	-1.159	-0.235	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,467 associations by consensus.

MTIF3 vs MTF2 — UCEC

Explore this scatter interactively →