Across TCGA patient cohorts, MTHFD2P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,702 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTHFD2P2-associated GO terms across cancer lineages are Recombinational repair, Positive regulation of TORC1 signaling, and Mismatch repair. Each is linked with MTHFD2P2 in more than 7 cancer types. Because this analysis shows association rather than direction, both MTHFD2P2-to-partner and partner-to-MTHFD2P2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD2P2→partner) and Y-score (partner→MTHFD2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Recombinational repair →	+0.137	+0.155	<.001	<.001	3	8
ESCA	Positive regulation of TORC1 signaling →	+0.118	+0.150	<.001	.004	3	7
ESCA	Mismatch repair →	+0.102	+0.143	<.001	.003	3	7
STAD	Glycerophospholipid metabolic process →	+0.089	+0.089	<.001	<.001	3	7
ESCA	Mitotic cell cycle checkpoint signaling →	+0.135	+0.088	<.001	.006	3	7
ESCA	tRNA processing →	+0.126	+0.179	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,702 associations by consensus.

Exploration

MTHFD2P2 survival (RNA) · tumor vs normal (RNA) · all MTHFD2P2 data types