MTHFD1L

Across TCGA patient cohorts, MTHFD1L RNA expression is significantly associated with the protein abundance of many other proteins, with 14,782 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MTHFD1L-associated proteins across cancer lineages are UTP4, DDX18, and HEATR1. Each is linked with MTHFD1L in more than 6 cancer types. Because this analysis shows association rather than direction, both MTHFD1L-to-partner and partner-to-MTHFD1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTHFD1L versus UTP4 in HNSC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD1L→partner) and Y-score (partner→MTHFD1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UTP4 →	+0.375	+0.872	<.001	.001	3	7
LUAD	DDX18 →	+0.444	+0.453	<.001	<.001	3	6
LUAD	HEATR1 →	+0.400	+0.516	<.001	<.001	3	6
LUAD	ANLN →	+1.046	+0.518	<.001	<.001	3	6
BRCA	PURA →	-0.351	-0.905	<.001	<.001	3	6
LUAD	WDR75 →	+0.424	+0.494	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,782 associations by consensus.

MTHFD1L vs UTP4 — HNSC

Explore this scatter interactively →