MTFR2

Across TCGA patient cohorts, MTFR2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,036 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MTFR2-associated genes across cancer lineages are GLS, LAMB4, and SEC14L2. Each is linked with MTFR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTFR2-to-partner and partner-to-MTFR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTFR2 versus GLS in UCEC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTFR2→partner) and Y-score (partner→MTFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GLS →	+0.902	+0.635	.009	.005	3	2
UCEC	LAMB4 →	-0.857	-0.742	.002	.002	3	2
UCEC	SEC14L2 →	-0.668	-0.579	.001	<.001	3	1
UCEC	TTLL1 →	-0.918	-0.579	<.001	<.001	3	1
UCEC	SAMD15 →	-2.144	-0.579	<.001	<.001	3	1
UCEC	PGRMC1 →	-0.830	-0.579	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,036 associations by consensus.

MTFR2 vs GLS — UCEC

Explore this scatter interactively →