MTDHP4

Across TCGA patient cohorts, MTDHP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,844 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTDHP4-associated GO terms across cancer lineages are Positive regulation of DNA repair, tRNA metabolic process, and Protein peptidyl-prolyl isomerization. Each is linked with MTDHP4 in more than 19 cancer types. Because this analysis shows association rather than direction, both MTDHP4-to-partner and partner-to-MTDHP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by MTDHP4-low versus MTDHP4-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTDHP4→partner) and Y-score (partner→MTDHP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of DNA repair →	+0.052	+0.377	.005	.003	2	20
ESCA	tRNA metabolic process →	+0.049	+0.253	.002	.001	2	19
STAD	Protein peptidyl-prolyl isomerization →	+0.056	+0.201	<.001	<.001	3	17
DLBC	Positive regulation of DNA-templated transcription, elongation →	+0.072	+0.443	<.001	<.001	3	17
DLBC	Regulation of DNA-templated transcription elongation →	+0.064	+0.339	.002	.006	3	16
STAD	Macromolecule methylation →	+0.040	+0.144	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,844 associations by consensus.

Positive regulation of DNA repair by MTDHP4 expression — DLBC

Explore this box plot interactively →