MTCYBP24

Across TCGA pan-cancer cohorts, MTCYBP24 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MTCYBP24 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MTCYBP24 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCYBP24 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LAML show a favorable association.

UCEC, STAD, and UCS are the cancer types where MTCYBP24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.555	0.768	.001	90	view →
STAD	DFS	Tertile	II,III,IV	0.322	0.639	<.001	74	view →
UCS	DFS	Tertile	II,III,IV	0.154	0.495	.002	54	view →
LUSC	DFS	Tertile	II,III,IV	0.834	0.671	.009	45	view →
UVM	DFS	Tertile	All	0.362	0.616	.014	36	view →
LAML	DFS	Median	All	0.492	0.253	.002	30	view →
READ	DFS	Tertile	IV	0.261	0.681	.009	24	view →
DLBC	DFS	Tertile	III,IV	0.070	0.855	.008	21	view →
ESCA	DFS	Quartile	III,IV	0.648	0.229	.011	19	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
LIHC	OS	Tertile	All	0.659	0.800	.003	12	view →
ACC	DFS	Tertile	All	0.759	0.522	.027	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MTCYBP24–UCEC (DFS)

Open the UCEC breakdown →