Across TCGA pan-cancer cohorts, MTCYBP24 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MTCYBP24’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MTCYBP24 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTCYBP24 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.
LIHC, THCA, and KIRC are the cancer types where MTCYBP24 tumor–normal differential expression is most reproducible.