MTCYBP22

Across TCGA pan-cancer cohorts, MTCYBP22 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MTCYBP22 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MTCYBP22 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MTCYBP22 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and LUSC are the cancer types where MTCYBP22 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.865	0.417	.004	90	view →
HNSC	DFS	Tertile	All	0.505	0.286	.001	72	view →
LUSC	DFS	Tertile	III,IV	0.580	0.232	.008	48	view →
OV	DFS	Quartile	II,III,IV	0.300	0.399	.002	42	view →
STAD	OS	Quartile	III,IV	0.472	0.726	.010	25	view →
BLCA	DFS	Tertile	All	0.694	0.436	.024	24	view →
LUAD	DFS	Tertile	III,IV	0.812	0.214	.001	24	view →
UCS	DFS	Tertile	IV	0.996	0.570	.039	18	view →
SARC	DFS	Tertile	All	0.512	0.655	.033	15	view →
LIHC	DFS	Tertile	III,IV	0.654	0.329	.042	12	view →
SKCM	DFS	Tertile	IV	0.040	0.432	.038	9	view →
UVM	DFS	Tertile	III,IV	0.129	0.673	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MTCYBP22–UCEC (DFS)

Open the UCEC breakdown →