MTCYBP18

Across TCGA pan-cancer cohorts, MTCYBP18 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated MTCYBP18 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher MTCYBP18 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MTCYBP18 expression acts as an unfavorable survival marker, although some lineages such as LUSC and KIRP show a favorable association.

LUSC, KIRP, and BLCA are the cancer types where MTCYBP18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	II,III,IV	0.815	0.615	<.001	90	view →
KIRP	OS	Tertile	II,III,IV	1.000	0.203	<.001	70	view →
BLCA	DFS	Median	All	0.713	0.470	.002	48	view →
LAML	DFS	Tertile	All	0.467	0.210	.003	32	view →
PAAD	OS	Median	All	0.615	0.339	.008	25	view →
UCS	OS	Tertile	IV	0.844	0.206	.024	24	view →
ACC	DFS	Median	All	0.626	0.299	.001	24	view →
DLBC	DFS	Median	II,III,IV	0.580	1.000	.013	19	view →
KICH	OS	Quartile	All	0.434	1.000	.009	18	view →
LGG	DFS	Quartile	All	0.645	0.878	.002	18	view →
THYM	OS	Median	All	0.921	1.000	.013	12	view →
HNSC	DFS	Quartile	IV	0.712	0.531	.009	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

MTCYBP18–LUSC (DFS)

Open the LUSC breakdown →