MTCO3P8

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MTCO3P8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,883 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTCO3P8-associated GO terms across cancer lineages are Proton transmembrane transport, Cellular respiration, and Aerobic respiration. Each is linked with MTCO3P8 in more than 11 cancer types. Because this analysis shows association rather than direction, both MTCO3P8-to-partner and partner-to-MTCO3P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton transmembrane transport grouped by MTCO3P8-low versus MTCO3P8-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO3P8→partner) and Y-score (partner→MTCO3P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAProton transmembrane transport →+0.048+0.112<.001.005212
STADCellular respiration →+0.052+0.107<.001<.001311
STADAerobic respiration →+0.057+0.123<.001<.001311
ESCAATP synthesis coupled electron transport →+0.063+0.123.001.001311
STADOxidative phosphorylation →+0.062+0.117<.001<.001310
ESCAMitochondrial electron transport, NADH to ubiquinone →+0.062+0.115<.001.002310
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,883 associations by consensus.

Proton transmembrane transport by MTCO3P8 expression — ESCA

Box plot of Proton transmembrane transport in MTCO3P8-low vs MTCO3P8-high samples in ESCA.

Explore this box plot interactively →

Exploration