MTCO3P8

Across TCGA pan-cancer cohorts, MTCO3P8 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MTCO3P8 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher MTCO3P8 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MTCO3P8 expression acts as an unfavorable survival marker, although some lineages such as ESCA and ACC show a favorable association.

ESCA, KIRC, and ACC are the cancer types where MTCO3P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	III,IV	0.584	0.300	.002	39	view →
KIRC	DFS	Quartile	III,IV	0.654	0.764	.007	33	view →
ACC	DFS	Tertile	II,III,IV	0.767	0.463	.021	33	view →
HNSC	DFS	Tertile	IV	0.676	0.274	.004	30	view →
UCEC	OS	Tertile	III,IV	0.286	0.632	.013	30	view →
READ	DFS	Tertile	II,III,IV	0.964	0.756	.018	15	view →
STAD	DFS	Median	IV	0.205	0.604	.026	12	view →
GBM	DFS	Quartile	All	0.150	0.241	.026	6	view →
SKCM	OS	Tertile	All	0.684	0.344	.013	6	view →
THCA	DFS	Tertile	IV	0.601	0.963	.007	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MTCO3P8–ESCA (OS)

Open the ESCA breakdown →