Across TCGA pan-cancer cohorts, MTCO3P40 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MTCO3P40’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MTCO3P40 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTCO3P40 is over-expressed in tumor.

LIHC, HNSC, and LUAD are the cancer types where MTCO3P40 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO3P40 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.036	.003	4	view →
HNSC	All	II,III,IV	+0.040	.026	2	view →
LUAD	Male	All	+0.042	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MTCO3P40 RNA expression & survival · all MTCO3P40 data types