Q-omics provides the consensus-scored MTCO3P40 profile across patient tissues and cancer cell-line models. MTCO3P40 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, MTCO3P40 is differentially expressed in 3, with the highest sampling consensus in LIHC. Additionally, MTCO3P40 RNA expression shows 6,271 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UCS, LIHC, and STAD as cancer lineages where MTCO3P40 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO3P40 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO3P40 survival associations across molecular data types. MTCO3P40 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO3P40 RNA expression–survival associations across cancer types. High MTCO3P40 expression shows unfavorable associations in UCS, LUAD, UVM, MESO, PAAD and KIRC. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .016). Together, the overview and detailed table identify UCS as the clearest survival context for MTCO3P40 RNA expression.
This table summarizes MTCO3P40 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in LIHC for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO3P40. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO3P40 shows higher tumor expression in LIHC, HNSC and LUAD. The LIHC box plot shows higher MTCO3P40 RNA expression in tumor versus normal tissue (log2 FC = +0.036, t-test p = .003).
This table shows molecular features associated with MTCO3P40 in patient tissues and cancer cell lines. In patient samples, MTCO3P40 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
